Alcohol's Impact on the Liver
📌 Excessive alcohol consumption causes inflammation (radang) in liver cells, processed via the enzyme alcohol dehydrogenase which converts alcohol to acetaldehyde.
🔥 Prolonged inflammation can lead to cell death (diver impairment) or hepatitis.
📉 The liver metabolizes alcohol, and overconsumption stresses this system, leading to damage.

Alcohol's Effect on Metabolism and Nutrient Absorption
📌 Continuous alcohol use erodes the mucosa of the digestive system, disrupting nutrient absorption.
🩸 Deficiencies in essential nutrients like iron (zat besi) can lead to anemia.
🧠 Impaired absorption of Vitamin B1 (thiamine) affects the nervous system, potentially causing memory impairment.
💊 Supplementation with iron (e.g., hematinik) and thiamine replacement can help restore normal function if absorption is compromised.

Alcohol and Cardiovascular System
⬇️ Alcohol can cause a decrease in blood pressure, termed hypotension, when consumed in excess.
💔 While some hypothesize low-dose alcohol is protective, recent evidence suggests chronic heavy drinking can harm the heart, leading to arrhythmia (irregular heartbeat).

Gastrointestinal and Appetite Effects
🔥 Alcohol is corrosive and can worsen existing conditions like peptic ulcer disease, potentially causing internal bleeding.
📉 Alcohol damages taste receptor cells, reducing the ability to enjoy food, leading to decreased appetite and potential weight loss initially.
💧 Severe liver damage (failure) reduces albumin production, leading to fluid retention (edema), causing swelling in the legs (pitting edema) and ascites (fluid in the abdomen).

Neurological and Addiction Aspects
😵 Acute intoxication causes disorientation, confusion, irrational behavior, and sometimes aggression.
🧠 Chronic use damages the reward system in the brain, which normally stimulates endorphins for pleasure (euphoria).
📉 Over time, this damage requires higher doses for the same effect (tolerance), eventually leading to severe withdrawal syndrome (seizures, hallucinations) if consumption stops.
🧠 Long-term, chronic alcohol use can cause cerebral atrophy (brain shrinkage) and lead to alcoholic dementia, similar to Alzheimer's disease.

Gender Differences in Tolerance and Safe Limits
♀️ For non-Muslim populations, the recommended safe weekly limit for women is 14 units.
♂️ For men, the recommended safe weekly limit is 21 units.

Dietary Management for Liver Impairment
🛑 Individuals with liver failure must reduce or stop continuous alcohol intake.
🚫 Patients with liver impairment are advised to limit oily foods and high-protein foods because the damaged liver struggles to metabolize these substances effectively.

Key Points & Insights
➡️ Excessive alcohol consumption directly damages the liver via inflammation and can lead to hepatitis and cell death.
➡️ Supplementation of Iron and Vitamin B1 (thiamine) is crucial for reversing deficiencies caused by alcohol-induced absorption issues, such as anemia and nerve impairment.
➡️ Chronic alcohol use permanently damages the brain's reward system, leading to dependency and potentially irreversible conditions like alcoholic dementia due to cerebral atrophy.
➡️ Safe consumption guidelines suggest limiting intake to no more than 21 units/week for men and 14 units/week for women.

📸 Video summarized with SummaryTube.com on Jan 13, 2026, 09:50 UTC