This video provides a guide on calculating drug dosages for pediatric patients (infants and children) and demonstrates the correct setup and use of syringe pumps and infusion (IV) pumps for administration.

Drug Dosage Calculation (Pediatrics)
📌 Example 1 (Oral Antibiotic): Calculated the required dose for a 10 kg, 10-month-old baby receiving Ampicillin syrup ($7.5 \text{ mg/kg/dose}$). The required dose was $75 \text{ mg}$, resulting in the need to administer $\mathbf{3 \text{ mL}}$ of the available $125 \text{ mg}/5 \text{ mL}$ suspension.
📌 Example 2 (Intravenous Antibiotic): Calculated the volume for a $4 \text{ kg}$, 1-month-old infant receiving $200 \text{ mg}$ IV daily (administered once daily in this calculation). The $1 \text{ G} (1000 \text{ mg})$ vial was diluted with $5 \text{ mL}$ of sterile water ($\text{aquades}$). The formula used was: (Dose Prescribed $\times$ Diluent Volume) / Stock Dose, resulting in $\mathbf{1 \text{ mL}}$ to be administered.

IV Fluid Calculation and Infusion Pump Setup (Infus Pump)
📌 Maintenance Fluid Calculation (22 kg, 4-year-old child): Used the standard weight-based formula: $100 \text{ mL/kg}$ for the first $10 \text{ kg}$, $50 \text{ mL/kg}$ for the next $10 \text{ kg}$, and $20 \text{ mL/kg}$ for remaining weight. This resulted in a total daily maintenance fluid requirement of $\mathbf{1540 \text{ mL}}$ over 24 hours.
📌 Drop Rate Setting: Calculated the infusion rate using the formula: (Total Fluid $\times$ Drop Factor) / (Time in hours $\times 60$ minutes). Using a standard macro drip factor (assumed to be 20 drops/mL for calculation simplification, though the speaker sets $60$ in the formula for macro drip, leading to $\mathbf{6 \text{ drops/minute}}$ when dividing $1540 \text{ mL}$ by $24 \times 60$). This rate ($\mathbf{6 \text{ gtt/min}}$) is then set on the infusion pump.

Syringe Pump Setup and Calculation
📌 Syringe Pump Drug Calculation: Used for drugs requiring small, precise, slow infusions. Example: Chloramphenicol ($100 \text{ mg/day}$ given $4$ times daily, so $25 \text{ mg}$ per dose). With a stock dose of $250 \text{ mg}$ diluted in $50 \text{ mL}$, the calculation determined that $\mathbf{5 \text{ mL}}$ needed to be administered over $\mathbf{60 \text{ minutes}}$ (1 hour).
📌 Syringe Pump Preparation: The process involved diluting the drug ($5 \text{ mL}$ of drug solution) into a larger volume of diluent ($45 \text{ mL}$ of $\text{aquades}$) to reach the total $50 \text{ mL}$ volume needed for administration. This $50 \text{ mL}$ is loaded into the syringe pump.
📌 Syringe Pump Setting: The rate was set based on the calculation: $\mathbf{5 \text{ mL}}$ volume to be delivered over $\mathbf{1 \text{ hour}}$ (or $5 \text{ mL/hr}$ rate if the pump is volumetric).

Key Points & Insights
➡️ Always verify dosage calculations before administering medication to pediatric patients, especially infants and neonates.
➡️ For oral medication calculation verification, ensure the calculated volume in $\text{mL}$ matches the volume drawn using the appropriate syringe size (e.g., $3 \text{ mL}$ syringe).
➡️ When using an Infusion Pump, carefully check for any air bubbles within the tubing before starting the infusion to prevent air embolism risk.
➡️ Syringe pumps are preferred for drugs requiring precise, low-dose rates delivered over extended periods.

📸 Video summarized with SummaryTube.com on Oct 08, 2025, 07:25 UTC