Vitamin B5 (Pantothenic Acid) - usmle Quick review

Vitamin B5 (Pantothenic Acid) Overview
🔬 Pantothenic acid is also known as Vitamin B5 or the chick anti-dermatitis factor.
🧬 Its biologically active form is Coenzyme A (CoA).
👑 The richest known source of Vitamin B5 is royal jelly, alongside biotin.

Sources and Daily Requirements
🥚 Sources include liver, egg yolk, cereals, legumes, milk, and chicken.
👶 Daily requirements vary: Adults need approximately 5 to 12 mg/day, infants need 1-2 mg/day, and children need 4 to 5 mg/day.

Functions of Pantothenic Acid
🔗 Essential for the formation of active acetate (acetyl-CoA) and active succinate (succinyl-CoA).
🍔 Plays a role in the synthesis of heme, fatty acids, and steroids.
🔥 Participates directly in the beta-oxidation of fatty acids.

Deficiency Symptoms
🔥 Deficiency primarily leads to the burning feet syndrome.
💇 Other symptoms include dermatitis, alopecia (hair loss), and adrenal insufficiency.

Key Points & Insights
➡️ Vitamin B5's primary function involves forming acetyl-CoA and succinyl-CoA.
➡️ Deficiency symptoms are significant, including burning feet syndrome and adrenal insufficiency.
➡️ Ensure adequate intake, especially for adults needing 5-12 mg daily, as it is crucial for energy metabolism (fatty acid oxidation).

📸 Video summarized with SummaryTube.com on Nov 12, 2025, 18:51 UTC